Topical gel contains %1 curcumin as nanoliposome (active ingredient of rhizome of Curcuma longa)
Curcumin (Diferuloylmethane), a polyphenol from the diarylheptanoids group, is the principal curcuminoid of turmeric, known as Curcuma longa belonging to the Zinger family. In combination with other main curcuminoids including desmethoxycurcumin, bis-desmethoxycurcumin, they form 3-5% of dried turmeric powder.
Pharmacological effects and Indications:
The rhizome of Curcuma longa has been used as a healer agent in the form of salve and ointment traditionally. It has been also used for bacterial and fungous infections such as tinea topically. Nowadays it is proved that these extra effects are related to antioxidant; anti-inflammatory, anti-microbial and anti-fungal effects of curcuminoids in curcuma longa rhizomes.
Topical Gel of Sinanomin:
Used as improver of inflammation, pain and wound in dermatological conditions due to burn, insect bites, injury and diabetic neuropathy.
It´s useful for skin sensitivity and inflammatory diseases such as itching, burning, Eczema, Psoriasis and Acne.
It is effective in relieving muscle and joint pain.
It is effective for alleviating of Gingivitis and Aphthous.
Mechanism of action:
The anti-inflammatory effect of curcumin is most likely mediated through its ability to inhibit cyclooxygenase-2 (COX-2), lipoxygenase (LOX), and inducible nitric oxide synthase (iNOS). COX-2, LOX, and iNOS are important enzymes that mediate inflammatory processes.
Curcumin has an important role in acceleration of wound healing and prevention of scar through inhibiting phosphorylase kinase enzyme and NFkB and TGFB with preventing reproduction of fibroblasts and decreasing inflammatory reactions.
Advantages of Nanoliposomal gel of curcumin:
Curcumin is insoluble in water which restrics usage of curcumin in the form of topical.
Encapsulation of curcumin in liposomal nanoparticles has solved this problem. Furthermore it can increase permeability and skin absorption of curcumin snd its resistance versus decomposition due to the light , too.
This product isn’t greasy and is washable with water.
Necessary information before using this medicine:
Read entire leaflet carefully before you start your treatment with this medicine.
If you have any further questions, consult with your doctor or pharmacist.
If you are sensitive to turmeric and other substance of gel, don’t use this product.
Your skin becomes yellow temporary after using.
Test this gel on the small part of your arm or behind the auricle before first consumption and if you haven’t any sensitivity, use it according to instructions.
Don’t use this product in your eyes.
Proper use of this medicine:
Apply enough Sinanomin gel in a thin layer three times a day on clean skin and damaged areas. It is best to use with cotton in damaged areas.
You can use more times if needed.
Don’t wash the affected areas up to 2 hours after the application of sinanomin gel.
It isn’t reported any side effects until now.
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